[This is preliminary documentation and subject to change.]
When plots are added to the plot surface, the axes they are attached to are immediately modified to reflect data of the plot. If AutoScaleAutoGeneratedAxes is true when a plot is added, the axes will be turned in to auto scaling ones if they are not already [tick marks, tick text and label size scaled to size of plot surface]. If false, axes will not be autoscaling.
IPlotSurface2D.AutoScaleAutoGeneratedAxes
PlotSurface2D Class | NPlot.Windows Namespace